HPA Brain Atlas
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The Human Protein Atlas (HPA) is a Swedish-based program started in 2003 with the aim to map all the human proteins in cells, tissues and organs using integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics and systems biology. All the data in the knowledge resource is open access to allow scientists both in academia and industry to freely access the data for exploration of the human proteome.
"The Brain Atlas explores the protein expression in the mammalian brain by integration of data from three mammalian species (human, pig and mouse). Transcriptomics data is combined with antibody-based protein localization in human samples and whole mouse brain. Protein-coding human genes (and one-to-one orthologues in pig and mouse) is provided with a brain-centric summary page, showing available expression data (mRNA) for brain samples grouped into 10 main brain regions, as well as data for pituitary gland, retina, corpus callosum and spinal cord. Series of sections, representing the whole mouse brain, analyzed for 300 genes are available as large 100 megapixel immunofluorescence images with microscopic resolution to explore the protein location in mouse brain (also summarized into 127 regions of interest). A selection of human localization data is also imported/linked from the Tissue Atlas and summarized on the Brain Atlas. "